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Analysis of BRAF(V600E) mutation and DNA methylation improves the diagnostics of thyroid fine needle aspiration biopsies

BACKGROUND: Thyroid nodules with indeterminate cytological features on fine needle aspiration biopsy specimens (FNABs) have a ~20% risk of thyroid cancer. BRAF( V600E ) mutation and DNA methylation are useful markers to distinguish malignant thyroid neoplasm from benign. The aim of this study was to...

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Detalles Bibliográficos
Autores principales: Zhang, Bingfei, Liu, Shu, Zhang, Zhaoxia, Wei, Jing, Qu, Yiping, Wu, Kexia, Yang, Qi, Hou, Peng, Shi, Bingyin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944809/
https://www.ncbi.nlm.nih.gov/pubmed/24588959
http://dx.doi.org/10.1186/1746-1596-9-45