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The Copper-Responsive RicR Regulon Contributes to Mycobacterium tuberculosis Virulence

As with most life on Earth, the transition metal copper (Cu) is essential for the viability of the human pathogen Mycobacterium tuberculosis. However, infected hosts can also use Cu to control microbial growth. Several Cu-responsive pathways are present in M. tuberculosis, including the regulated in...

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Detalles Bibliográficos
Autores principales: Shi, Xiaoshan, Festa, Richard A., Ioerger, Thomas R., Butler-Wu, Susan, Sacchettini, James C., Darwin, K. Heran, Samanovic, Marie I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944814/
https://www.ncbi.nlm.nih.gov/pubmed/24549843
http://dx.doi.org/10.1128/mBio.00876-13