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An Innate Immunity-Regulating Virulence Determinant Is Uniquely Encoded within the Andes Virus Nucleocapsid Protein

Andes virus (ANDV) is the only hantavirus known to spread from person to person and shown to cause highly lethal hantavirus pulmonary syndrome (HPS) in patients and Syrian hamsters. Hantaviruses replicate in human endothelial cells and accomplish this by restricting the early induction of beta inter...

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Detalles Bibliográficos
Autores principales: Cimica, Velasco, Dalrymple, Nadine A., Roth, Eric, Nasonov, Aleksandr, Mackow, Erich R.
Formato: Online Artigo Texto
Idioma:English
Publicado: American Society of Microbiology 2014
Materias:
Acceso en liña:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944819/
https://www.ncbi.nlm.nih.gov/pubmed/24549848
http://dx.doi.org/10.1128/mBio.01088-13