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Dual Role for Inflammasome Sensors NLRP1 and NLRP3 in Murine Resistance to Toxoplasma gondii

Induction of immunity that limits Toxoplasma gondii infection in mice is critically dependent on the activation of the innate immune response. In this study, we investigated the role of cytoplasmic nucleotide-binding domain and leucine-rich repeat containing a pyrin domain (NLRP) inflammasome sensor...

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Detalles Bibliográficos
Autores principales: Gorfu, Gezahegn, Cirelli, Kimberly M., Melo, Mariane B., Mayer-Barber, Katrin, Crown, Devorah, Koller, Beverly H., Masters, Seth, Sher, Alan, Leppla, Stephen H., Moayeri, Mahtab, Saeij, Jeroen P. J., Grigg, Michael E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944820/
https://www.ncbi.nlm.nih.gov/pubmed/24549849
http://dx.doi.org/10.1128/mBio.01117-13