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Differential Stability of the Crystallographic Interfaces of Mu- and Kappa-Opioid Receptors

The recent mu-opioid receptor (MOPr) and kappa-opioid receptor (KOPr) crystal structures have inspired hypotheses of physiologically relevant dimerization contacts, specifically: a closely packed interface involving transmembrane (TM) helices TM5 and TM6, and a less compact interface, involving TM1,...

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Detalles Bibliográficos
Autores principales: Johnston, Jennifer M., Filizola, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944890/
https://www.ncbi.nlm.nih.gov/pubmed/24651466
http://dx.doi.org/10.1371/journal.pone.0090694