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Differential Stability of the Crystallographic Interfaces of Mu- and Kappa-Opioid Receptors
The recent mu-opioid receptor (MOPr) and kappa-opioid receptor (KOPr) crystal structures have inspired hypotheses of physiologically relevant dimerization contacts, specifically: a closely packed interface involving transmembrane (TM) helices TM5 and TM6, and a less compact interface, involving TM1,...
Autores principales: | Johnston, Jennifer M., Filizola, Marta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944890/ https://www.ncbi.nlm.nih.gov/pubmed/24651466 http://dx.doi.org/10.1371/journal.pone.0090694 |
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