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An optogenetic gene expression system with rapid activation and deactivation kinetics

Optogenetic gene expression systems can control transcription with spatial and temporal detail unequaled with traditional inducible promoter systems. However, current eukaryotic light-gated transcription systems are limited by toxicity, dynamic range, or slow activation/deactivation. Here we present...

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Detalles Bibliográficos
Autores principales: Motta-Mena, Laura B., Reade, Anna, Mallory, Michael J., Glantz, Spencer, Weiner, Orion D., Lynch, Kristen W., Gardner, Kevin H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944926/
https://www.ncbi.nlm.nih.gov/pubmed/24413462
http://dx.doi.org/10.1038/nchembio.1430