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Resolution of central nervous system astrocytic and endothelial sources of CCL2 gene expression during evolving neuroinflammation

BACKGROUND: The chemokine CCL2 is a critical mediator of neuroinflammation in diseases such as multiple sclerosis (MS) and its animal model, experimental autoimmune encephalomyelitis (EAE). CCL2 drives mononuclear cell infiltration into the central nervous system (CNS), alters expression and distrib...

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Detalles Bibliográficos
Autores principales: Shrestha, Bandana, Ge, Shujun, Pachter, Joel S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944978/
https://www.ncbi.nlm.nih.gov/pubmed/24589378
http://dx.doi.org/10.1186/2045-8118-11-6