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Expression Level and Subcellular Localization of Heme Oxygenase-1 Modulates Its Cytoprotective Properties in Response to Lung Injury: A Mouse Model

Premature infants exposed to hyperoxia suffer acute and long-term pulmonary consequences. Nevertheless, neonates survive hyperoxia better than adults. The factors contributing to neonatal hyperoxic tolerance are not fully elucidated. In contrast to adults, heme oxygenase (HO)-1, an endoplasmic retic...

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Detalles Bibliográficos
Autores principales: Namba, Fumihiko, Go, Hayato, Murphy, Jennifer A., La, Ping, Yang, Guang, Sengupta, Shaon, Fernando, Amal P., Yohannes, Mekdes, Biswas, Chhanda, Wehrli, Suzanne L., Dennery, Phyllis A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944979/
https://www.ncbi.nlm.nih.gov/pubmed/24599172
http://dx.doi.org/10.1371/journal.pone.0090936