An investigation of the impact of futility analysis in publicly funded trials

BACKGROUND: Publicly funded trials regularly fail to recruit their target sample size or find a significant positive result. Adaptive clinical trials which may partly mediate against the problems are not often applied. In this paper we investigate the potential of a form of adaption in a clinical tr...

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Detalles Bibliográficos
Autores principales: Sully, Benjamin GO, Julious, Steven A, Nicholl, Jon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3945066/
https://www.ncbi.nlm.nih.gov/pubmed/24533447
http://dx.doi.org/10.1186/1745-6215-15-61

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3945066/
https://www.ncbi.nlm.nih.gov/pubmed/24533447
http://dx.doi.org/10.1186/1745-6215-15-61

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