An ER Complex of ODR-4 and ODR-8/Ufm1 Specific Protease 2 Promotes GPCR Maturation by a Ufm1-Independent Mechanism

Despite the importance of G-protein coupled receptors (GPCRs) their biogenesis is poorly understood. Like vertebrates, C. elegans uses a large family of GPCRs as chemoreceptors. A subset of these receptors, such as ODR-10, requires the odr-4 and odr-8 genes to be appropriately localized to sensory c...

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Detalles Bibliográficos
Autores principales: Chen, Changchun, Itakura, Eisuke, Weber, Katherine P., Hegde, Ramanujan S., de Bono, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3945108/
https://www.ncbi.nlm.nih.gov/pubmed/24603482
http://dx.doi.org/10.1371/journal.pgen.1004082

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3945108/
https://www.ncbi.nlm.nih.gov/pubmed/24603482
http://dx.doi.org/10.1371/journal.pgen.1004082

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