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An ER Complex of ODR-4 and ODR-8/Ufm1 Specific Protease 2 Promotes GPCR Maturation by a Ufm1-Independent Mechanism
Despite the importance of G-protein coupled receptors (GPCRs) their biogenesis is poorly understood. Like vertebrates, C. elegans uses a large family of GPCRs as chemoreceptors. A subset of these receptors, such as ODR-10, requires the odr-4 and odr-8 genes to be appropriately localized to sensory c...
Autores principales: | Chen, Changchun, Itakura, Eisuke, Weber, Katherine P., Hegde, Ramanujan S., de Bono, Mario |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3945108/ https://www.ncbi.nlm.nih.gov/pubmed/24603482 http://dx.doi.org/10.1371/journal.pgen.1004082 |
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