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The Functional Consequences of Variation in Transcription Factor Binding

One goal of human genetics is to understand how the information for precise and dynamic gene expression programs is encoded in the genome. The interactions of transcription factors (TFs) with DNA regulatory elements clearly play an important role in determining gene expression outputs, yet the regul...

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Detalles Bibliográficos
Autores principales: Cusanovich, Darren A., Pavlovic, Bryan, Pritchard, Jonathan K., Gilad, Yoav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3945204/
https://www.ncbi.nlm.nih.gov/pubmed/24603674
http://dx.doi.org/10.1371/journal.pgen.1004226