Dysregulated Estrogen Receptor Signaling in the Hypothalamic-Pituitary-Ovarian Axis Leads to Ovarian Epithelial Tumorigenesis in Mice

The etiology of ovarian epithelial cancer is poorly understood, mainly due to the lack of an appropriate experimental model for studying the onset and progression of this disease. We have created a mutant mouse model in which aberrant estrogen receptor alpha (ERα) signaling in the hypothalamic-pitui...

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Detalles Bibliográficos
Autores principales: Laws, Mary J., Kannan, Athilakshmi, Pawar, Sandeep, Haschek, Wanda M., Bagchi, Milan K., Bagchi, Indrani C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3945209/
https://www.ncbi.nlm.nih.gov/pubmed/24603706
http://dx.doi.org/10.1371/journal.pgen.1004230

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3945209/
https://www.ncbi.nlm.nih.gov/pubmed/24603706
http://dx.doi.org/10.1371/journal.pgen.1004230

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