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Differential Regulation of GABA(B) Receptor Trafficking by Different Modes of N-methyl-d-aspartate (NMDA) Receptor Signaling

Inhibitory GABA(B) receptors (GABA(B)Rs) can down-regulate most excitatory synapses in the CNS by reducing postsynaptic excitability. Functional GABA(B)Rs are heterodimers of GABA(B1) and GABA(B2) subunits and here we show that the trafficking and surface expression of GABA(B)Rs is differentially re...

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Detalles Bibliográficos
Autores principales: Kantamneni, Sriharsha, Gonzàlez-Gonzàlez, Immaculada M., Luo, Jia, Cimarosti, Helena, Jacobs, Susan C., Jaafari, Nadia, Henley, Jeremy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3945329/
https://www.ncbi.nlm.nih.gov/pubmed/24425870
http://dx.doi.org/10.1074/jbc.M113.487348