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Bone morphogenetic protein signalling suppresses wound-induced skin repair by inhibiting keratinocyte proliferation and migration

Bone morphogenetic protein (BMP) signalling plays a key role in the control of skin development and postnatal remodelling by regulating keratinocyte proliferation, differentiation and apoptosis. To study the role of BMPs in wound-induced epidermal repair, we used transgenic mice overexpressing the B...

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Detalles Bibliográficos
Autores principales: Lewis, Christopher J., Mardaryev, Andrei N., Poterlowicz, Krzysztof, Sharova, Tatyana Y., Aziz, Ahmar, Sharpe, David T., Botchkareva, Natalia V., Sharov, Andrey A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3945401/
https://www.ncbi.nlm.nih.gov/pubmed/24126843
http://dx.doi.org/10.1038/jid.2013.419