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ERK8 is a negative regulator of O-GalNAc glycosylation and cell migration

ER O-glycosylation can be induced through relocalisation GalNAc-Transferases from the Golgi. This process markedly stimulates cell migration and is constitutively activated in more than 60% of breast carcinomas. How this activation is achieved remains unclear. Here, we screened 948 signalling genes...

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Detalles Bibliográficos
Autores principales: Chia, Joanne, Tham, Keit Min, Gill, David James, Bard-Chapeau, Emilie Anne, Bard, Frederic A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3945522/
https://www.ncbi.nlm.nih.gov/pubmed/24618899
http://dx.doi.org/10.7554/eLife.01828