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ERK8 is a negative regulator of O-GalNAc glycosylation and cell migration
ER O-glycosylation can be induced through relocalisation GalNAc-Transferases from the Golgi. This process markedly stimulates cell migration and is constitutively activated in more than 60% of breast carcinomas. How this activation is achieved remains unclear. Here, we screened 948 signalling genes...
Autores principales: | Chia, Joanne, Tham, Keit Min, Gill, David James, Bard-Chapeau, Emilie Anne, Bard, Frederic A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3945522/ https://www.ncbi.nlm.nih.gov/pubmed/24618899 http://dx.doi.org/10.7554/eLife.01828 |
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