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Tumor-stroma metabolic relationship based on lactate shuttle can sustain prostate cancer progression

BACKGROUND: Cancer cell adopts peculiar metabolic strategies aimed to sustain the continuous proliferation in an environment characterized by relevant fluctuations in oxygen and nutrient levels. Monocarboxylate transporters MCT1 and MCT4 can drive such adaptation permitting the transport across plas...

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Detalles Bibliográficos
Autores principales: Sanità, Patrizia, Capulli, Mattia, Teti, Anna, Galatioto, Giuseppe Paradiso, Vicentini, Carlo, Chiarugi, Paola, Bologna, Mauro, Angelucci, Adriano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3945608/
https://www.ncbi.nlm.nih.gov/pubmed/24597899
http://dx.doi.org/10.1186/1471-2407-14-154