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Tumor-stroma metabolic relationship based on lactate shuttle can sustain prostate cancer progression
BACKGROUND: Cancer cell adopts peculiar metabolic strategies aimed to sustain the continuous proliferation in an environment characterized by relevant fluctuations in oxygen and nutrient levels. Monocarboxylate transporters MCT1 and MCT4 can drive such adaptation permitting the transport across plas...
Autores principales: | Sanità, Patrizia, Capulli, Mattia, Teti, Anna, Galatioto, Giuseppe Paradiso, Vicentini, Carlo, Chiarugi, Paola, Bologna, Mauro, Angelucci, Adriano |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3945608/ https://www.ncbi.nlm.nih.gov/pubmed/24597899 http://dx.doi.org/10.1186/1471-2407-14-154 |
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