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The Acute Effects of Low-Dose TNF-α on Glucose Metabolism and β-Cell Function in Humans

Type 2 diabetes is characterized by increased insulin resistance and impaired insulin secretion. Type 2 diabetes is also associated with low-grade inflammation and increased levels of proinflammatory cytokines such as TNF-α. TNF-α has been shown to impair peripheral insulin signaling in vitro and in...

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Detalles Bibliográficos
Autores principales: Ibfelt, Tobias, Fischer, Christian P., Plomgaard, Peter, van Hall, Gerrit, Pedersen, Bente Klarlund
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3945645/
https://www.ncbi.nlm.nih.gov/pubmed/24692847
http://dx.doi.org/10.1155/2014/295478