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Inflammatory and cytotoxic effects of acrolein, nicotine, acetylaldehyde and cigarette smoke extract on human nasal epithelial cells

BACKGROUND: Cigarette smoke induces a pro-inflammatory response in airway epithelial cells but it is not clear which of the various chemicals contained within cigarette smoke (CS) should be regarded as predominantly responsible for these effects. We hypothesised that acrolein, nicotine and acetylald...

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Detalles Bibliográficos
Autores principales: Comer, David M, Elborn, Joseph Stuart, Ennis, Madeleine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3945717/
https://www.ncbi.nlm.nih.gov/pubmed/24581246
http://dx.doi.org/10.1186/1471-2466-14-32