Thrombospondin-1 triggers macrophage IL-10 production and promotes resolution of experimental lung injury

Mononuclear phagocyte recognition of apoptotic cells triggering suppressive cytokine signaling is a key event in inflammation resolution from injury. Mice deficient in thrombospondin-1 (thbs1(−/−)), an extracellular matrix glycoprotein that bridges cell-cell interactions, are prone to LPS-induced lu...

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Detalles Bibliográficos
Autores principales: Zhao, Yani, Xiong, Zeyu, Lechner, Elizabeth J., Klenotic, Philip A., Hamburg, Brian J., Hulver, Mei, Khare, Anupriya, Oriss, Timothy, Mangalmurti, Nilam, Chan, Yvonne, Zhang, Yingze, Ross, Mark A., Stolz, Donna B., Rosengart, Matthew R., Pilewski, Joseph, Ray, Prabir, Ray, Anuradha, Silverstein, Roy L., Lee, Janet S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3945733/
https://www.ncbi.nlm.nih.gov/pubmed/24045574
http://dx.doi.org/10.1038/mi.2013.63

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3945733/
https://www.ncbi.nlm.nih.gov/pubmed/24045574
http://dx.doi.org/10.1038/mi.2013.63

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