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Kynurenines with Neuroactive and Redox Properties: Relevance to Aging and Brain Diseases

The kynurenine pathway (KP) is the main route of tryptophan degradation whose final product is NAD(+). The metabolism of tryptophan can be altered in ageing and with neurodegenerative process, leading to decreased biosynthesis of nicotinamide. This fact is very relevant considering that tryptophan i...

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Detalles Bibliográficos
Autores principales: Reyes Ocampo, Jazmin, Lugo Huitrón, Rafael, González-Esquivel, Dinora, Ugalde-Muñiz, Perla, Jiménez-Anguiano, Anabel, Pineda, Benjamín, Pedraza-Chaverri, José, Ríos, Camilo, Pérez de la Cruz, Verónica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3945746/
https://www.ncbi.nlm.nih.gov/pubmed/24693337
http://dx.doi.org/10.1155/2014/646909