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PTEN Regulates BCRP/ABCG2 and the Side Population through the PI3K/Akt Pathway in Chronic Myeloid Leukemia

A small population of cancer stem cells named the “side population” (SP) has been demonstrated to be responsible for the persistence of many solid tumors. However, the role of the SP in leukemic pathogenesis remains controversial. The resistance of leukemic stem cells to targeted therapies, such as...

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Detalles Bibliográficos
Autores principales: Huang, Fang-Fang, Zhang, Li, Wu, Deng-Shu, Yuan, Xiao-Yu, Chen, Fang-Ping, Zeng, Hui, Yu, Yan-Hui, Zhao, Xie-Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3945754/
https://www.ncbi.nlm.nih.gov/pubmed/24603487
http://dx.doi.org/10.1371/journal.pone.0088298