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Lipoxygenase Pathway Mediates Increases of Airway Resistance and Lung Inflation Induced by Exposure to Nanotitanium Dioxide in Rats

Nanotitanium dioxide particle (nTiO(2)) inhalation has been reported to induce lung parenchymal injury. After inhalation of nTiO(2), we monitored changes in 5-lipoxygenase, endothelial nitric oxide synthase (eNOS), and inducible nitric oxide synthase (iNOS) mRNA in rat lung tissue. Lung function par...

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Detalles Bibliográficos
Autores principales: Lee, Jyu-Feng, Tung, Shu-Ping, Wang, David, Yeh, Diana Yuwung, Fong, Yao, Young, Yu-Chung, Leu, Fur-Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3945789/
https://www.ncbi.nlm.nih.gov/pubmed/24693335
http://dx.doi.org/10.1155/2014/485604