Cargando…

Impaired glomerulogenesis and endothelial cell migration in Pkd1-deficient renal organ cultures

The PKD1 gene is essential for a number of biological functions, and its loss-of-function causes autosomal dominant polycystic kidney disease (ADPKD). The gene is developmentally regulated and believed to play an essential role in renal development. Previous studies have shown that manipulating muri...

Descripción completa

Detalles Bibliográficos
Autores principales: Rowe, Isaline, Chiaravalli, Marco, Piontek, Klaus B., Germino, Gregory G., Boletta, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3945815/
https://www.ncbi.nlm.nih.gov/pubmed/24472557
http://dx.doi.org/10.1016/j.bbrc.2014.01.068