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Impaired glomerulogenesis and endothelial cell migration in Pkd1-deficient renal organ cultures
The PKD1 gene is essential for a number of biological functions, and its loss-of-function causes autosomal dominant polycystic kidney disease (ADPKD). The gene is developmentally regulated and believed to play an essential role in renal development. Previous studies have shown that manipulating muri...
Autores principales: | Rowe, Isaline, Chiaravalli, Marco, Piontek, Klaus B., Germino, Gregory G., Boletta, Alessandra |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3945815/ https://www.ncbi.nlm.nih.gov/pubmed/24472557 http://dx.doi.org/10.1016/j.bbrc.2014.01.068 |
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