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Argonaute2 Mediates Compensatory Expansion of the Pancreatic β Cell

Pancreatic β cells adapt to compensate for increased metabolic demand during insulin resistance. Although the microRNA pathway has an essential role in β cell proliferation, the extent of its contribution is unclear. Here, we report that miR-184 is silenced in the pancreatic islets of insulin-resist...

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Detalles Bibliográficos
Autores principales: Tattikota, Sudhir G., Rathjen, Thomas, McAnulty, Sarah J., Wessels, Hans-Hermann, Akerman, Ildem, van de Bunt, Martijn, Hausser, Jean, Esguerra, Jonathan L.S., Musahl, Anne, Pandey, Amit K., You, Xintian, Chen, Wei, Herrera, Pedro L., Johnson, Paul R., O’Carroll, Donal, Eliasson, Lena, Zavolan, Mihaela, Gloyn, Anna L., Ferrer, Jorge, Shalom-Feuerstein, Ruby, Aberdam, Daniel, Poy, Matthew N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3945818/
https://www.ncbi.nlm.nih.gov/pubmed/24361012
http://dx.doi.org/10.1016/j.cmet.2013.11.015