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Ligand-Dependent Dynamics of the Active-Site Lid in Bacterial Dimethylarginine Dimethylaminohydrolase
[Image: see text] The dimethylarginine dimethylaminohydrolase (DDAH) enzyme family has been the subject of substantial investigation as a potential therapeutic target for the regulation of vascular tension. DDAH enzymes catalyze the conversion of asymmetric N(η),N(η)-dimethylarginine (ADMA) to l-cit...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American
Chemical Society
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3945819/ https://www.ncbi.nlm.nih.gov/pubmed/24484052 http://dx.doi.org/10.1021/bi4015924 |