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F-box Protein FBXL16 Binds PP2A-B55α and Regulates Differentiation of Embryonic Stem Cells along the FLK1+ Lineage

The programmed formation of specific tissues from embryonic stem cells is a major goal of regenerative medicine. To identify points of intervention in cardiac tissue formation, we performed an siRNA screen in murine embryonic stem cells to identify ubiquitin system genes that repress cardiovascular...

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Detalles Bibliográficos
Autores principales: Honarpour, Narimon, Rose, Christopher M., Brumbaugh, Justin, Anderson, Jody, Graham, Robert L. J., Sweredoski, Michael J., Hess, Sonja, Coon, Joshua J., Deshaies, Raymond J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3945908/
https://www.ncbi.nlm.nih.gov/pubmed/24390425
http://dx.doi.org/10.1074/mcp.M113.031765