A Selective Glutathione Probe based on AIE Fluorogen and its Application in Enzymatic Activity Assay

In this work, we design and synthesize a malonitrile-functionalized TPE derivative (TPE-DCV), which can react with thiol group through thiol-ene click reaction, leading to the fluorescence change of the system. Combined with the unique AIE property, TPE-DCV can selectively detect glutathione (GSH) b...

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Detalles Bibliográficos
Autores principales: Lou, Xiaoding, Hong, Yuning, Chen, Sijie, Leung, Chris Wai Tung, Zhao, Na, Situ, Bo, Lam, Jacky Wing Yip, Tang, Ben Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3945925/
https://www.ncbi.nlm.nih.gov/pubmed/24603274
http://dx.doi.org/10.1038/srep04272

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3945925/
https://www.ncbi.nlm.nih.gov/pubmed/24603274
http://dx.doi.org/10.1038/srep04272

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