The Key to the Extraordinary Thermal Stability of P. furiosus Holo-Rubredoxin: Iron Binding-Guided Packing of a Core Aromatic Cluster Responsible for High Kinetic Stability of the Native Structure

Pyrococcus furiosus rubredoxin (PfRd), a small, monomeric, 53 residues-long, iron-containing, electron-transfer protein of known structure is sometimes referred to as being the most structurally-stable protein known to man. Here, using a combination of mutational and spectroscopic (CD, fluorescence,...

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Detalles Bibliográficos
Autores principales: Prakash, Satya, Sundd, Monica, Guptasarma, Purnananda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3945938/
https://www.ncbi.nlm.nih.gov/pubmed/24603898
http://dx.doi.org/10.1371/journal.pone.0089703

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3945938/
https://www.ncbi.nlm.nih.gov/pubmed/24603898
http://dx.doi.org/10.1371/journal.pone.0089703

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