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Enamelin Is Critical for Ameloblast Integrity and Enamel Ultrastructure Formation

Mutations in the human enamelin gene cause autosomal dominant hypoplastic amelogenesis imperfecta in which the affected enamel is thin or absent. Study of enamelin knockout NLS-lacZ knockin mice revealed that mineralization along the distal membrane of ameloblast is deficient, resulting in no true e...

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Detalles Bibliográficos
Autores principales: Hu, Jan C.-C., Hu, Yuanyuan, Lu, Yuhe, Smith, Charles E., Lertlam, Rangsiyakorn, Wright, John Timothy, Suggs, Cynthia, McKee, Marc D., Beniash, Elia, Kabir, M. Enamul, Simmer, James P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3945975/
https://www.ncbi.nlm.nih.gov/pubmed/24603688
http://dx.doi.org/10.1371/journal.pone.0089303