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Enhancement of Cellular Antioxidant-Defence Preserves Diastolic Dysfunction via Regulation of Both Diastolic Zn(2+) and Ca(2+) and Prevention of RyR2-Leak in Hyperglycemic Cardiomyocytes

We examined whether cellular antioxidant-defence enhancement preserves diastolic dysfunction via regulation of both diastolic intracellular free Zn(2+) and Ca(2+) levels ([Zn(2+)](i) and [Ca(2+)](i)) levels N-acetyl cysteine (NAC) treatment (4 weeks) of diabetic rats preserved altered cellular redox...

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Detalles Bibliográficos
Autores principales: Tuncay, Erkan, Okatan, Esma N., Toy, Aysegul, Turan, Belma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3945998/
https://www.ncbi.nlm.nih.gov/pubmed/24693334
http://dx.doi.org/10.1155/2014/290381