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Enhancement of Cellular Antioxidant-Defence Preserves Diastolic Dysfunction via Regulation of Both Diastolic Zn(2+) and Ca(2+) and Prevention of RyR2-Leak in Hyperglycemic Cardiomyocytes
We examined whether cellular antioxidant-defence enhancement preserves diastolic dysfunction via regulation of both diastolic intracellular free Zn(2+) and Ca(2+) levels ([Zn(2+)](i) and [Ca(2+)](i)) levels N-acetyl cysteine (NAC) treatment (4 weeks) of diabetic rats preserved altered cellular redox...
Autores principales: | Tuncay, Erkan, Okatan, Esma N., Toy, Aysegul, Turan, Belma |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3945998/ https://www.ncbi.nlm.nih.gov/pubmed/24693334 http://dx.doi.org/10.1155/2014/290381 |
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