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Hepatic Hedgehog signaling contributes to the regulation of IGF1 and IGFBP1 serum levels
BACKGROUND: Hedgehog signaling plays an important role in embryonic development, organogenesis and cancer. In the adult liver, Hedgehog signaling in non-parenchymal cells has been found to play a role in certain disease states such as fibrosis and cirrhosis. However, whether the Hedgehog pathway is...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3946028/ https://www.ncbi.nlm.nih.gov/pubmed/24548465 http://dx.doi.org/10.1186/1478-811X-12-11 |