Effects of curcuminoids identified in rhizomes of Curcuma longa on BACE-1 inhibitory and behavioral activity and lifespan of Alzheimer’s disease Drosophila models

BACKGROUND: Alzheimer’s disease (AD) is the most common type of presenile and senile dementia. The human β-amyloid precursor cleavage enzyme (BACE-1) is a key enzyme responsible for amyloid plaque production, which implicates the progress and symptoms of AD. Here we assessed the anti-BACE-1 and beha...

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Detalles Bibliográficos
Autores principales: Wang, Xue, Kim, Jun-Ran, Lee, Seong-Baek, Kim, Young-Joon, Jung, Moon Young, Kwon, Hyung-Wook, Ahn, Young-Joon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3946151/
https://www.ncbi.nlm.nih.gov/pubmed/24597901
http://dx.doi.org/10.1186/1472-6882-14-88

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3946151/
https://www.ncbi.nlm.nih.gov/pubmed/24597901
http://dx.doi.org/10.1186/1472-6882-14-88

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