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A Functionally Significant Polymorphism in ID3 Is Associated with Human Coronary Pathology

AIMS: We previously identified association between the ID3 SNP rs11574 and carotid intima-media thickness in the Diabetes Heart Study, a predominantly White diabetic population. The nonsynonymous SNP rs11574 results in an amino acid substitution in the C-terminal region of ID3, attenuating the domin...

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Detalles Bibliográficos
Autores principales: Manichaikul, Ani, Rich, Stephen S., Perry, Heather, Yeboah, Joseph, Law, Michelle, Davis, Molly, Parker, Matthew, Ragosta, Michael, Connelly, Jessica J., McNamara, Coleen A., Taylor, Angela M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3946163/
https://www.ncbi.nlm.nih.gov/pubmed/24603695
http://dx.doi.org/10.1371/journal.pone.0090222