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Crystal Structures of the Novel Cytosolic 5′-Nucleotidase IIIB Explain Its Preference for m(7)GMP
5′-nucleotidases catalyze the hydrolytic dephosphorylation of nucleoside monophosphates. As catabolic enzymes they contribute significantly to the regulation of cellular nucleotide levels; misregulation of nucleotide metabolism and nucleotidase deficiencies are associated with a number of diseases....
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3946280/ https://www.ncbi.nlm.nih.gov/pubmed/24603684 http://dx.doi.org/10.1371/journal.pone.0090915 |