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Structural Basis of Lipid-Driven Conformational Transitions in the KvAP Voltage Sensing Domain
Voltage-gated ion channels respond to transmembrane electric fields through reorientations of the positively charged S4 helix within the voltage-sensing domain (VSD). Despite a wealth of structural and functional data, the details of this conformational change remain controversial. Recent electrophy...
Autores principales: | Li, Qufei, Wanderling, Sherry, Somponspisut, Pornthep, Perozo, Eduardo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3946318/ https://www.ncbi.nlm.nih.gov/pubmed/24413055 http://dx.doi.org/10.1038/nsmb.2747 |
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