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Modulation of T(reg) function improves adenovirus vector-mediated gene expression in the airway
Virus vector -mediated gene transfer has been developed as a treatment for cystic fibrosis (CF) airway disease, a lethal inherited disorder caused by somatic mutations in the CFTR gene. The pathological pro-inflammatory environment of CF as well as the naïve and adaptive immunity induced by the viru...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3946346/ https://www.ncbi.nlm.nih.gov/pubmed/24385144 http://dx.doi.org/10.1038/gt.2013.78 |