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Resveratrol Differentially Regulates NAMPT and SIRT1 in Hepatocarcinoma Cells and Primary Human Hepatocytes

Resveratrol is reported to possess chemotherapeutic properties in several cancers. In this study, we wanted to investigate the molecular mechanisms of resveratrol-induced cell cycle arrest and apoptosis as well as the impact of resveratrol on NAMPT and SIRT1 protein function and asked whether there...

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Detalles Bibliográficos
Autores principales: Schuster, Susanne, Penke, Melanie, Gorski, Theresa, Petzold-Quinque, Stefanie, Damm, Georg, Gebhardt, Rolf, Kiess, Wieland, Garten, Antje
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3946349/
https://www.ncbi.nlm.nih.gov/pubmed/24603648
http://dx.doi.org/10.1371/journal.pone.0091045