Post-Translational Regulation via Clp Protease Is Critical for Survival of Mycobacterium tuberculosis

Unlike most bacterial species, Mycobacterium tuberculosis depends on the Clp proteolysis system for survival even in in vitro conditions. We hypothesized that Clp is required for the physiologic turnover of mycobacterial proteins whose accumulation is deleterious to bacterial growth and survival. To...

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Detalles Bibliográficos
Autores principales: Raju, Ravikiran M., Jedrychowski, Mark P., Wei, Jun-Rong, Pinkham, Jessica T., Park, Annie S., O'Brien, Kathryn, Rehren, German, Schnappinger, Dirk, Gygi, Steven P., Rubin, Eric J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3946367/
https://www.ncbi.nlm.nih.gov/pubmed/24603869
http://dx.doi.org/10.1371/journal.ppat.1003994

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3946367/
https://www.ncbi.nlm.nih.gov/pubmed/24603869
http://dx.doi.org/10.1371/journal.ppat.1003994

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