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A Polysaccharide Virulence Factor from Aspergillus fumigatus Elicits Anti-inflammatory Effects through Induction of Interleukin-1 Receptor Antagonist

The galactosaminogalactan (GAG) is a cell wall component of Aspergillus fumigatus that has potent anti-inflammatory effects in mice. However, the mechanisms responsible for the anti-inflammatory property of GAG remain to be elucidated. In the present study we used in vitro PBMC stimulation assays to...

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Detalles Bibliográficos
Autores principales: Gresnigt, Mark S., Bozza, Silvia, Becker, Katharina L., Joosten, Leo A. B., Abdollahi-Roodsaz, Shahla, van der Berg, Wim B., Dinarello, Charles A., Netea, Mihai G., Fontaine, Thierry, De Luca, Antonella, Moretti, Silvia, Romani, Luigina, Latge, Jean-Paul, van de Veerdonk, Frank L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3946377/
https://www.ncbi.nlm.nih.gov/pubmed/24603878
http://dx.doi.org/10.1371/journal.ppat.1003936