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A Polysaccharide Virulence Factor from Aspergillus fumigatus Elicits Anti-inflammatory Effects through Induction of Interleukin-1 Receptor Antagonist
The galactosaminogalactan (GAG) is a cell wall component of Aspergillus fumigatus that has potent anti-inflammatory effects in mice. However, the mechanisms responsible for the anti-inflammatory property of GAG remain to be elucidated. In the present study we used in vitro PBMC stimulation assays to...
Autores principales: | Gresnigt, Mark S., Bozza, Silvia, Becker, Katharina L., Joosten, Leo A. B., Abdollahi-Roodsaz, Shahla, van der Berg, Wim B., Dinarello, Charles A., Netea, Mihai G., Fontaine, Thierry, De Luca, Antonella, Moretti, Silvia, Romani, Luigina, Latge, Jean-Paul, van de Veerdonk, Frank L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3946377/ https://www.ncbi.nlm.nih.gov/pubmed/24603878 http://dx.doi.org/10.1371/journal.ppat.1003936 |
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