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The Herpes Virus Fc Receptor gE-gI Mediates Antibody Bipolar Bridging to Clear Viral Antigens from the Cell Surface

The Herpes Simplex Virus 1 (HSV-1) glycoprotein gE-gI is a transmembrane Fc receptor found on the surface of infected cells and virions that binds human immunoglobulin G (hIgG). gE-gI can also participate in antibody bipolar bridging (ABB), a process by which the antigen-binding fragments (Fabs) of...

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Detalles Bibliográficos
Autores principales: Ndjamen, Blaise, Farley, Alexander H., Lee, Terri, Fraser, Scott E., Bjorkman, Pamela J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3946383/
https://www.ncbi.nlm.nih.gov/pubmed/24604090
http://dx.doi.org/10.1371/journal.ppat.1003961