Losartan reverses permissive epigenetic changes in renal glomeruli of diabetic db/db mice

Epigenetic mechanisms such as chromatin histone H3 lysine methylation and acetylation have been implicated in diabetic vascular complications. However, histone modification profiles at pathologic genes associated with diabetic nephropathy in vivo and their regulation by the angiotensin II type 1 rec...

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Detalles Bibliográficos
Autores principales: Reddy, Marpadga A., Sumanth, Putta, Lanting, Linda, Yuan, Hang, Wang, Mei, Mar, Daniel, Alpers, Charles E., Bomsztyk, Karol, Natarajan, Rama
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3946617/
https://www.ncbi.nlm.nih.gov/pubmed/24088954
http://dx.doi.org/10.1038/ki.2013.387

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3946617/
https://www.ncbi.nlm.nih.gov/pubmed/24088954
http://dx.doi.org/10.1038/ki.2013.387

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