Down-Regulation of the RNA Editing Enzyme ADAR2 Contributes to RGC Death in a Mouse Model of Glaucoma

Glaucoma is a progressive neurodegenerative disease of retinal ganglion cells (RGCs) associated with characteristic axon degeneration in the optic nerve. Excitotoxic damage due to increased Ca(2+) influx, possibly through NMDA-type glutamate receptors, has been proposed to be a cause of RGC dysfunct...

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Detalles Bibliográficos
Autores principales: Wang, Ai Ling, Carroll, Reed C., Nawy, Scott
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3946738/
https://www.ncbi.nlm.nih.gov/pubmed/24608178
http://dx.doi.org/10.1371/journal.pone.0091288

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3946738/
https://www.ncbi.nlm.nih.gov/pubmed/24608178
http://dx.doi.org/10.1371/journal.pone.0091288

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