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Preexisting CD4+ T-Cell Immunity in Human Population to Avian Influenza H7N9 Virus: Whole Proteome-Wide Immunoinformatics Analyses

In 2013, a novel avian influenza H7N9 virus was identified in human in China. The antigenically distinct H7N9 surface glycoproteins raised concerns about lack of cross-protective neutralizing antibodies. Epitope-specific preexisting T-cell immunity was one of the protective mechanisms in pandemic 20...

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Detalles Bibliográficos
Autores principales: Duvvuri, Venkata R., Duvvuri, Bhargavi, Alice, Christilda, Wu, Gillian E., Gubbay, Jonathan B., Wu, Jianhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3946744/
https://www.ncbi.nlm.nih.gov/pubmed/24609014
http://dx.doi.org/10.1371/journal.pone.0091273